供biovendor MxA Protein Human ELISA 欣博盛供
貨號:RD194349200R
名稱:MxA Protein Human ELISA
規(guī)格:96 wells (1 kit)
產品描述:
人MXA蛋白(粘液virus抗性蛋白1)是MX1基因的產物,是由662個氨基酸殘基組成的76kDa蛋白,屬于大GTPase的動態(tài)超家族。MXA蛋白在細胞對抗各種virus(包括流感、副流感、麻疹、柯薩奇、乙型肝炎virus和thogotovirus)的抗virus活性中起著重要作用。virus在其生命周期的早期、宿主細胞進入后不久和基因組擴增前被MXA蛋白抑制。小鼠mxa(mx1-gtpase)聚集在細胞核內,與核體結合,抑制已知在細胞核內復制的流感virus和thogotovirus。人MXA蛋白也聚集在細胞質和內質網中。內質網的膜室似乎提供了一個促進virus目標識別的相互作用平臺。MXA似乎通過感知和捕獲核衣殼樣結構來檢測virusinfect。因此,virus成分無法用于產生新的virus顆粒。virusMXA蛋白的表達僅由干擾素α和干擾素β以劑量依賴性方式誘導,而不是由干擾素γ、IL-1、TNFα或其他細胞因子誘導。在臨床診斷中,MXA蛋白作為virusinfect的標志物可能比其他誘導蛋白(如2',5’-寡腺苷酸合成酶)更具優(yōu)勢,因為其基礎濃度非常低,半衰期較長。一些臨床研究報告了MXA蛋白在外周血單個核細胞中的表達可能作為區(qū)分virus性和細菌性疾病的標志物,以及在慢性virus性肝炎和多發(fā)性硬化的干擾素treatment過程中I型干擾素生物可利用性的可靠標志物。
特點:
It is intended for research use only.
The total assay time is less than 3 hours.
The kit measures MxA protein in whole blood (cell lysate).
Assay format is 96 wells.
Standard is native MxA protein based.
Components of the kit are provided ready to use, concentrated or lyophilized
類型:Sandwich ELISA, Biotin-labelled antibody
別名:Myxovirus resistance protein 1
物種:Human
校準范圍:0.375–12 ng/ml
檢測限:0.001 ng/ml
回收率:99,70%
稀釋線性:95,60%
應用:Whole blood
運輸:At ambient temperature. Upon receipt, store the product at the temperature recommended below.
儲存/到期:Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
試劑盒組成:
Antibody Coated Microtiter Strips 96 wells
Biotin Labelled Antibody 1.3 ml
Streptavidin-HRP Conjugate 13 ml
Master Standard 2 vials
Dilution Buffer 2 x 15 ml
Wash Solution Conc.(10x) 100 ml
Substrate Solution 13 ml
Stop Solution 13 ml
Product Data Sheet + Certificate of Analysis 1 pc
產品覆蓋以下研究領域, 主要提供ELISA試劑盒,重組蛋白及相關抗體
凋亡(Apoptosis) |
糖尿病-胰島素、C-肽、胰島素原 (Diabetology - Insulin, C-Peptide, Proinsulin) |
肌生長調控 (Muscle Growth Control) |
自身免疫 (Autoimmunity) |
糖尿病-其他相關產品 (Diabetology - Other Relevant Products) |
神經組織標志物 (Neural Tissue Markers) |
血壓調節(jié)和NO代謝 (Blood Pressure Regulation And NO Metabolism) |
能量代謝和體重調節(jié) (Energy Metabolism And Body Weight Regulation) |
腫瘤學 (Oncology) |
骨與軟骨代謝 (Bone And Cartilage Metabolism) |
生長hormone和生長因子相關 (Growth Hormone And Factor-related Products) |
氧化應激 (Oxidative Stress) |
心血管疾病 (Cardiovascular Disease) |
免疫應答、infect和炎癥反應 (Immune Response, Infection And Inflammation) |
胰調控分子 (Pancreatic Regulatory Molecules) |
細胞粘連蛋白 (Cell Adhesion Proteins) |
免疫學 (Immunology) |
腎臟疾病 (Renal Disease) |
細胞因子、趨化因子及相關分子 (Cytokines And Chemokines And Related Molecules) |
鐵代謝(Iron Metabolism) |
生殖 (Reproduction) |
糖尿病-自身免疫 (Diabetology – Autoimmunity) |
脂蛋白代謝 (Lipoprotein Metabolism) |
細胞表面蛋白 (Cell Surface Proteins (sCD) ) |
分泌型磷脂酶A2 (Secreted Phospholipases A2 show all) |
血清學 (Serology) |
類固醇hormone (Steroid Hormones) |
移植 (Transplantation) |
動物相關研究 (Animal Studies) |
其他研究領域 (Others) |
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